⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197196 | 0.69 | PCSK9 (0.60) | — | |
| SCHEMBL143814 | 0.67 | — | — | |
| SCHEMBL196709 | 0.65 | — | — | |
| SCHEMBL3766047 | 0.65 | — | — | |
| SCHEMBL12074519 | 0.65 | — | — | |
| SCHEMBL4282205 | 0.65 | — | — | |
| SCHEMBL15272985 | 0.65 | — | — | |
| SCHEMBL3092636 | 0.65 | — | — | |
| SCHEMBL2971700 | 0.65 | — | — | |
| SCHEMBL12754884 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | SALTIGO GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
| CN-101300209-A | Nickel-or iron-catalyzed carbon-carbon coupling of arylenes, alkenes and alkynes | SALTIGO GMBH (DE) | 2008-11-05 | — | — | CN | disclosed |
| EP-1924539-A1 | NICKEL OR IRON CATALYSED CARBON-CARBON COUPLING REACTION OF ARYLENES, ALKENES AND ALKINES | Saltigo GmbH (DE) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007031511-A1 | NICKEL OR IRON CATALYSED CARBON-CARBON COUPLING REACTION OF ARYLENES, ALKENES AND ALKINES | SALTIGO GMBH (DE) | 2007-03-22 | — | — | WO | disclosed |
| US-6884801-B1 | Imidazoline derivatives as alpha-1A adrenoceptor ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |
| WO-2000061134-A9 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARM (GB) | 2004-04-22 | — | — | WO | disclosed |
| US-6716878-B1 | BACTERICIDE, ANTIPROTOZOAL; VANCOMYCIN RESISTANT ENTEROCOCCI AND BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA, METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; HYDROXAMIC ACID AND N-FORMYL SUBTITUTED ALKYLAMIDES | VERNALIS (OXFORD) LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |
| US-6509474-B1 | Metallization with lithium in ether solvent in presence of conjugated diene hydrogen acceptor | CHEMETALL GMBH (DE) | 2003-01-21 | — | — | US | disclosed |
| EP-1124819-B1 | METHOD OF LITHIATING FIVE-MEMBERED HETEROCYCLES | CHEMETALL GMBH (DE) | 2003-01-08 | — | — | EP | disclosed |
| EP-1169031-A1 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000061134-A1 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-19 | — | — | WO | disclosed |
| EP-0146348-B1 | SUBSTITUTED NAPHTHALENES, INDOLES, BENZOFURANS AND BENZOTHIOPHENES AS LIPOXYGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4737519-A | Substituted naphthalenes, indoles, benzofurans, and benzothiophenes as lipoxygenase inhibitors | THE UPJOHN COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| EP-0146348-A2 | Substituted naphthalenes, indoles, benzofurans and benzothiophenes as lipoxygenase inhibitors | THE UPJOHN COMPANY (US) | 1985-06-26 | — | — | EP | disclosed |
| US-4173640-A | Hypotensive perhydro naphthalene pentol derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-11-06 | — | — | US | disclosed |