Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | INMT | O95050 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22824362 | 0.84 | PCSK9 (0.48) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL6444709 | 0.81 | PCSK9 (0.73) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL31729550 | 0.81 | PCSK9 (0.46) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL439225 | 0.77 | KDM4E (0.49) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL1026027 | 0.75 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL11357896 | 0.75 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL3188837 | 0.75 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL19007341 | 0.75 | ALDH1A1 (0.48) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL6067970 | 0.75 | ALDH1A1 (0.44) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL11359663 | 0.75 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10315975-B2 | Method for the hydroformylation of 2-substituted butadienes and the production of secondary products thereof, especially ambrox | BASF SE (DE) | 2019-06-11 | — | — | US | disclosed |
| US-10175557-B2 | Optical wavelength conversion element containing ionic liquid, and article equipped with said optical wavelength conversion element | NIPPON KAYAKU KABUSHIKIKAISHA (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20170084758-A1 | Optical Wavelength Conversion Element Containing Ionic Liquid, And Article Equipped With Said Optical Wavelength Conversion Element | NIPPON KAYAKU KABUSHIKIKAISHA (JP) | 2017-03-23 | — | — | US | disclosed |
| EP-2390241-B1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-8598349-B2 | Method for manufacturing conjugated aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-03 | — | — | US | disclosed |
| US-8293905-B2 | Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-23 | — | — | US | disclosed |
| US-8088883-B2 | Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-03 | — | — | US | disclosed |
| EP-2390241-A1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2011-11-30 | — | — | EP | disclosed |
| US-20110275859-A1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED | 2011-11-10 | — | — | US | disclosed |
| US-20110256790-A1 | THERMAL INSULATION CONTAINING SUPPLEMENTAL INFRARED RADIATION ABSORBING MATERIAL | SAINT-GOBAIN ISOVER (FR) | 2011-10-20 | — | — | US | disclosed |
| US-20110046336-A1 | TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED | 2011-02-24 | — | — | US | disclosed |
| US-20100292481-A1 | METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-11-18 | — | — | US | disclosed |
| EP-2233459-A1 | METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2010-09-29 | — | — | EP | disclosed |
| US-20100184978-A1 | BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-2192124-A1 | TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX | Sumitomo Chemical Company, Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| EP-2172470-A1 | BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | Sumitomo Chemical Company, Limited (JP) | 2010-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10315975-B2 | Method for the hydroformylation of 2-substituted butadienes and the production of secondary products thereof, especially ambrox | ALOX12, ALOX15, ALOX5 | PCSK9 1536/4885ALDH1A1 683/4885CYP2A6 200/4885 |
| US-20110275859-A1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | C9, H1-10, CYP1A1 | PCSK9 1405/4885ALDH1A1 46/4885CYP2A6 182/4885 |
| US-20110046336-A1 | TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | C9, C5, AP1M1 | PCSK9 3665/4885ALDH1A1 974/4885CYP2A6 878/4885 |
| US-20100184978-A1 | BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | C9, C5, AP2M1 | PCSK9 3372/4885ALDH1A1 1092/4885CYP2A6 490/4885 |
| US-20100292481-A1 | METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND | TYR, PAH, AHR | PCSK9 1358/4885ALDH1A1 816/4885CYP2A6 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.