SCHEMBL2998560

SCHEMBL2998560

O=C(/C=C/c1ccc(CCCCc2ccc(N3C(=O)C=CC3=O)cc2)cc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.52
ALDH1A1 P00352 5/20 0.52
KMT2A Q03164 5/20 0.52
MEN1 O00255 3/20 0.52
NPSR1 Q6W5P4 1/20 0.52
MAOB P27338 4/20 0.50
BCHE P06276 3/20 0.50
HDAC3 O15379 3/20 0.50
HDAC4 P56524 3/20 0.50
HDAC1 Q13547 3/20 0.50
HDAC7 Q8WUI4 3/20 0.50
HDAC2 Q92769 3/20 0.50
HDAC10 Q969S8 3/20 0.50
HDAC11 Q96DB2 3/20 0.50
HDAC8 Q9BY41 3/20 0.50
HDAC6 Q9UBN7 3/20 0.50
HDAC9 Q9UKV0 3/20 0.50
HDAC5 Q9UQL6 3/20 0.50
LMNA P02545 2/20 0.50
PLIN1 O60240 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2998570 1.00 MAPT (0.52) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL2999419 0.99 MGLL (0.51) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL2990669 0.99 MGLL (0.51) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL2990675 0.99 MGLL (0.51) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL2999423 0.99 MGLL (0.51) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL2989413 0.99 MGLL (0.51) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL3002222 0.99 MGLL (0.51) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL2989410 0.99 MGLL (0.51) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL3002499 0.99 MGLL (0.51) MAPTALDH1A1KMT2AMEN1NPSR1
SCHEMBL3002217 0.99 MGLL (0.51) MAPTALDH1A1KMT2AMEN1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7787085-B2 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2010-08-31 US disclosed
US-20080123046-A1 OPTICAL ALIGNMENT METHOD AND LIQUID CRYSTAL DISPLAY ELEMENT JSR CORPORATION (JP) 2008-05-29 US disclosed
US-7074344-B2 Liquid crystal aligning agent and liquid crystal display element JSR CORPORATION (JP) 2006-07-11 US disclosed
US-20050259203-A1 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2005-11-24 US disclosed
EP-1353217-A1 Optical alignment method and liquid crystal display element JSR Corporation (JP) 2003-10-15 EP disclosed
US-20030087045-A1 Liquid crystal aligning agent and liquid crystal display element JSR CORPORATION (JP) 2003-05-08 US disclosed