Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.69 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.63 |
| ▸ | AR | P10275 | 4/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.52 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | IL1B | P01584 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986789 | 1.00 | CRBN (0.69) | CRBNDDB1ARBTKIKZF3 | |
| SCHEMBL29986419 | 0.93 | CRBN (0.70) | CRBNDDB1ARBTKIKZF3 | |
| SCHEMBL25172415 | 0.92 | CRBN (0.80) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30400867 | 0.92 | CRBN (0.80) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30985066 | 0.91 | CRBN (0.64) | CRBNDDB1ARBTKIKZF3 | |
| SCHEMBL30984987 | 0.89 | CRBN (0.64) | CRBNDDB1ARBTKIKZF3 | |
| SCHEMBL30985136 | 0.87 | CRBN (0.62) | CRBNDDB1ARIKZF3ALDH1A1 | |
| SCHEMBL25939463 | 0.87 | CRBN (0.76) | CRBNDDB1ARBTKIKZF3 | |
| SCHEMBL23139076 | 0.86 | CRBN (0.71) | CRBNDDB1ARIKZF3ALDH1A1 | |
| SCHEMBL23125158 | 0.86 | CRBN (0.71) | CRBNDDB1ARBTKIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251224-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2022-12-01 | — | — | WO | disclosed |