Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.70 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.64 |
| ▸ | AR | P10275 | 3/20 | 0.53 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | IL1B | P01584 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985066 | 0.95 | CRBN (0.64) | CRBNDDB1ARIKZF3ALDH1A1 | |
| SCHEMBL29986108 | 0.93 | CRBN (0.69) | CRBNDDB1ARIKZF3ALDH1A1 | |
| SCHEMBL29986789 | 0.93 | CRBN (0.69) | CRBNDDB1ARIKZF3ALDH1A1 | |
| SCHEMBL30400867 | 0.93 | CRBN (0.80) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL25172415 | 0.93 | CRBN (0.80) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30985055 | 0.93 | CRBN (0.65) | CRBNDDB1ARIKZF3ALDH1A1 | |
| SCHEMBL30985040 | 0.93 | CRBN (0.65) | CRBNDDB1ARIKZF3ALDH1A1 | |
| SCHEMBL30984751 | 0.92 | CRBN (0.60) | CRBNDDB1ARBTK | |
| SCHEMBL29986720 | 0.91 | CRBN (0.68) | CRBNDDB1ARIKZF3ALDH1A1 | |
| SCHEMBL30984987 | 0.90 | CRBN (0.64) | CRBNDDB1ARIKZF3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251224-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2022-12-01 | — | — | WO | disclosed |