Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814422 | 1.00 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR | |
| SCHEMBL24816196 | 0.90 | TAS1R3 (0.50) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR | |
| SCHEMBL29986069 | 0.90 | TAS1R3 (0.50) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR | |
| SCHEMBL24814454 | 0.87 | DPP9 (0.44) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR | |
| SCHEMBL24814425 | 0.86 | GAA (0.47) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR | |
| SCHEMBL29986907 | 0.86 | GAA (0.47) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR | |
| SCHEMBL24814755 | 0.81 | POLB (0.40) | ALDH1A1TSHRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL29986546 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL24817130 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL24815800 | 0.80 | SMN1; SMN2 (0.49) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |