⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952777 | 0.79 | TSHR (0.56) | — | |
| SCHEMBL252121 | 0.79 | TSHR (0.56) | — | |
| SCHEMBL8060600 | 0.79 | TSHR (0.56) | — | |
| SCHEMBL26091851 | 0.77 | SMN1; SMN2 (0.68) | — | |
| SCHEMBL29988 | 0.77 | — | — | |
| SCHEMBL208522 | 0.77 | — | — | |
| SCHEMBL17105684 | 0.74 | — | — | |
| SCHEMBL290484 | 0.74 | — | — | |
| SCHEMBL5138597 | 0.74 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL363871 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 9167 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151759-A1 | HETEROCYCLIC COMPOUNDS AS PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | claimed |
| EP-4396187-A1 | NAPHTHYRIDINE COMPOUNDS AS INHIBITORS OF KRAS | Incyte Corporation (US) | 2024-07-10 | — | — | EP | claimed |
| US-12030883-B2 | Hetero-tricyclic compounds as inhibitors of KRAS | INCYTE CORPORATION (US) | 2024-07-09 | — | — | US | claimed |
| US-12012409-B2 | Bicyclic heterocycles as FGFR inhibitors | INCYTE CORPORATION (US) | 2024-06-18 | — | — | US | claimed |
| US-12006320-B2 | Heterocyclic derivatives as PI3K inhibitors | INCYTE CORPORATION (US) | 2024-06-11 | — | — | US | claimed |
| US-20240180954-A1 | CATIONIC LIPID | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | claimed |
| US-11999740-B2 | Fused pyrazine derivatives as A2A / A2B inhibitors | INCYTE CORPORATION (US) | 2024-06-04 | — | — | US | claimed |
| US-11999752-B2 | Vinyl imidazole compounds as inhibitors of KRAS | INCYTE CORPORATION (US) | 2024-06-04 | — | — | US | claimed |
| WO-2024109707-A1 | FUSED RING PYRIDONE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | 合肥医工医药股份有限公司 | 2024-05-30 | — | — | WO | claimed |
| US-20240174664-A1 | BICYCLIC AMINES AS CDK2 INHIBITORS | INCYTE CORPORATION | 2024-05-30 | — | — | US | claimed |
| US-4083847-A | Transiently water-soluble disperse mono-azo dyes containing a diamino-methylene-carbacyl group | CIBA-GEIGY CORPORATION (US) | 1978-04-11 | — | — | US | claimed |
| US-4078146-A | TREATMENT OF CARDIO-VASCULAR DISORDERS | AKTIEBOLAGET HASSLE (SW) | 1978-03-07 | — | — | US | claimed |
| US-4076819-A | ANTIINFLAMMATORY AGENTS, INHIBITOR OF BLOOD PLATELET AGGREGATION | PARCOR (FR) | 1978-02-28 | — | — | US | claimed |
| US-4052379-A | DYES FROM TRIFLUOROMETHYL-2-AMINOBENZOTHIAZOLE DIAZO COMPONENTS | EASTMAN KODAK COMPANY (US) | 1977-10-04 | — | — | US | claimed |
| US-4012372-A | MONOAZO DISPERSE DYES | EASTMAN KODAK COMPANY (US) | 1977-03-15 | — | — | US | claimed |
| US-4006178-A | Process for the manufacture of dicyanovinyl compounds | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | claimed |
| US-RE29119-E | 7-Pyridinium methyl carboxyl derivatives of 7-amino-cephalosporanic acid | CIBA-GEIGY CORPORATION (US) | 1977-01-18 | — | — | US | claimed |
| US-3987026-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | claimed |
| US-3980634-A | Phthalimidyl-azo aniline type compounds and polyester fibers dyed therewith | EASTMAN KODAK COMPANY (US) | 1976-09-14 | — | — | US | claimed |
| US-3951978-A | ANALGESIC, ANTIARRHYTHMIC, CENTRAL NERVOUS DEPRESSANT | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-04-20 | — | — | US | claimed |