SCHEMBL252121

SCHEMBL252121

C=CCNC(=O)NCC=C

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
MAPT P10636 1/20 0.56
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 4/20 0.48
FAAH O00519 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
RAB9A P51151 1/20 0.43
HPGD P15428 3/20 0.42
LMNA P02545 2/20 0.42
HTT P42858 1/20 0.42
CYP1A2 P05177 1/20 0.41
PKM P14618 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8060600 1.00 TSHR (0.56) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL11367872 0.89
SCHEMBL5138597 0.88 SMN1; SMN2 (0.52) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL3182230 0.87
SCHEMBL17859667 0.86 SMN1; SMN2 (0.50) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL17859666 0.86 SMN1; SMN2 (0.50) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL3795914 0.86
SCHEMBL24132826 0.85 EPHX1 (0.52) TSHRSMN1; SMN2MAPTKMT2AFAAH
SCHEMBL4577617 0.85 TSHR (0.45) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL4577611 0.85 TSHR (0.45) TSHRSMN1; SMN2MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122025784-A Flame-retardant polymer electrolyte material based on Lewis acid-base synergistic regulation and preparation method thereof 石河子大学 2026-05-12 CN claimed
US-20260125496-A1 MONOMERS AND CURABLE COMPOSITIONS FOR CRYSTALLINITY CONTROL IN POLYMERIC MATERIALS FOR 3D-PRINTED DENTAL DEVICES ALIGN TECHNOLOGY INC (US) 2026-05-07 US claimed
EP-4049841-B1 HYBRID RESIN COMPOSITION CUBICURE GMBH (AT) 2026-03-18 EP claimed
EP-4704757-A1 SEMICRYSTALLINE SULFUR CONTAINING POLYMERS FOR ORTHODONTIC APPLICATIONS Align Technology, Inc. (US) 2026-03-11 EP claimed
EP-4174115-B1 RADIATION CROSS-LINKING BOOSTERS FOR ALIPHATIC POLYAMIDES THUERINGISCHES INST FUER TEXTIL UND KUNSTSTOFF FORSCHUNG E V (DE) 2025-12-10 EP claimed
WO-2025235302-A1 POLYMERIC COMPOSITIONS THAT INCLUDE UREA REPEAT GROUPS PPG INDUSTRIES OHIO, INC. (US) 2025-11-13 WO claimed
EP-4073172-B1 METHOD FOR PREPARING AN INVERSE LATEX FOR COSMETIC COMPOSITION COMBINING EDDS AS SEQUESTERING AGENT AND A POLYELECTROLYTE COMPRISING AMPS AND ACRYLAMIDE SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2025-11-12 EP claimed
US-20250319013-A1 THICKENING COMPOSITION FOR THICKENING POLAR OR NON-POLAR OILS SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2025-10-16 US claimed
US-12390987-B2 Hybrid resin composition for the 3D-printing of objects CUBICURE GMBH (AT) 2025-08-19 US claimed
CN-114650803-B Cosmetic composition in the form of compacted, impact-resistant powder 化工产品开发公司SEPPIC 2025-03-14 CN claimed
WO-1994009000-A1 QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1994-04-28 WO claimed
EP-0186361-B2 Thickeners for thickening aqueous media SCOTT BADER CO (GB) 1994-04-27 EP claimed
WO-1993025386-A1 THERMALLY RESISTANT GLASS ARTICLE ENSIGN-BICKFORD COATINGS COMPANY (US) 1993-12-23 WO claimed
US-5225473-A For bioelectrodes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-07-06 US claimed
EP-0186361-B1 THICKENERS FOR THICKENING AQUEOUS MEDIA SCOTT BADER COMPANY LIMITED (GB) 1990-09-12 EP claimed
EP-0186361-A2 Thickeners for thickening aqueous media SCOTT BADER COMPANY LIMITED (GB) 1986-07-02 EP claimed
US-4485031-A FOR REACTION INJECTION MOLDING POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1984-11-27 US claimed
EP-0029891-B1 PAINT COMPOSITIONS HAVING WET ADHESION CHARACTERISTICS AIR PRODUCTS AND CHEMICALS, INC. (US) 1983-08-17 EP claimed
US-4302375-A VINYL ACETATE LATEX WITH COPOLYMERIZED DIALLYL UREA AIR PRODUCTS AND CHEMICALS, INC. (US) 1981-11-24 US claimed
EP-0029891-A2 Paint compositions having wet adhesion characteristics AIR PRODUCTS AND CHEMICALS, INC. (US) 1981-06-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125496-A1 MONOMERS AND CURABLE COMPOSITIONS FOR CRYSTALLINITY CONTROL IN POLYMERIC MATERIALS FOR 3D-PRINTED DENTAL DEVICES SMCHD1, SMC4, SMC3 TSHR 2031/4885SMN1; SMN2 1219/4885MAPT 2819/4885
US-20250319013-A1 THICKENING COMPOSITION FOR THICKENING POLAR OR NON-POLAR OILS PHOSPHO1, ELOVL5, PARG TSHR 4044/4885SMN1; SMN2 3576/4885MAPT 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.