⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299825 | 0.75 | — | — | |
| SCHEMBL11454513 | 0.72 | — | — | |
| SCHEMBL300345 | 0.71 | — | — | |
| SCHEMBL300304 | 0.71 | GRIA1 (0.36) | — | |
| SCHEMBL300221 | 0.69 | GRIA1 (0.39) | — | |
| SCHEMBL299849 | 0.69 | GRIA1 (0.39) | — | |
| SCHEMBL300159 | 0.69 | GRIA1 (0.39) | — | |
| SCHEMBL299722 | 0.69 | GRIA1 (0.39) | — | |
| SCHEMBL27822246 | 0.69 | CA5A (0.33) | — | |
| SCHEMBL8981447 | 0.69 | PTGS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168751-B1 | WATER SOLUBLE TRIPHENEDIOXAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-08 | — | — | EP | claimed |
| EP-0187456-A1 | Cephalosporin derivatives | ICI PHARMA (FR) | 1986-07-16 | — | — | EP | claimed |
| US-8492567-B2 | (Poly)Aminoalkylaminoalkylamide, alkyl-urea, or alkyl-sulfonamide derivatives of epipodophyllotoxin, a process for preparing them, and application thereof in therapy as anticancer agents | PIERRE FABRE MEDICAMENT (FR) | 2013-07-23 | — | — | US | disclosed |
| US-20120283281-A1 | NEW (POLY)AMINOALKYLAMINOALKYLAMIDE, ALKYL-UREA, OR ALKYL-SULFONAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN, A PROCESS FOR PREPARING THEM, AND APPLICATION THEREOF IN THERAPY AS ANTICANCER AGENTS | IMBERT THIERRY (FR) | 2012-11-08 | — | — | US | disclosed |
| US-8288567-B2 | (Poly) aminoalkylaminoalkylamide, alkyl-urea, or alkyl-sulfonamide derivatives of epipodophyllotoxin, a process for preparing them, and application thereof in therapy as anticancer agents | PIERRE FABRE MEDICAMENT (FR) | 2012-10-16 | — | — | US | disclosed |
| CN-101180333-B | Slipping and leveling agent | CIBA SC HOLDING AG | 2012-06-13 | — | — | CN | disclosed |
| EP-1501897-B1 | METHOD FOR THE PRODUCTION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIIMIDES AND PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIANHYDRIDE AND NAPHTALENE-1,8-DICARBOXYLIMIDES | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-20110172257-A1 | (POLY) AMINOALKYLAMINOALKYLAMIDE, ALKYL-UREA, OR ALKYL-SULFONAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN, A PROCESS FOR PREPARING THEM, AND APPLICATION THEREOF IN THERAPY AS ANTICANCER AGENTS | PIERRE FABRE MEDICAMENT (FR) | 2011-07-14 | — | — | US | disclosed |
| US-7807836-B2 | Preparation of perylen-3,4:9,10-tetracarboxylic dianhydride and also of naphtalene-1,8-dicarboximides | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-05 | — | — | US | disclosed |
| US-20080161569-A1 | PREPARATION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC DIANHYDRIDE AND ALSO OF NAPHTALENE-1,8-DICARBOXIMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-03 | — | — | US | disclosed |
| US-7393956-B2 | Method for the production of perylen-3,4:9,10-tetracarboxylic acid diimides and perylen-3,4:9,10-tetracarboxylic acid dianhydride and naphtalene-1,8-dicarboxylimides | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-01 | — | — | US | disclosed |
| EP-0215355-A2 | Erythromycin derivative and process for preparing the same | KITASATO KENKYUSHO (JP) | 1987-03-25 | — | — | EP | disclosed |
| EP-0213617-A2 | Digestive tract contractile motion stimulant | KITASATO KENKYUSHO (JP) | 1987-03-11 | — | — | EP | disclosed |
| EP-0187456-A1 | Cephalosporin derivatives | ICI PHARMA (FR) | 1986-07-16 | — | — | EP | disclosed |
| EP-0098433-A2 | Beta-lactam antibiotics, process for their preparation and preparations containing them | BAYER AG (DE) | 1984-01-18 | — | — | EP | disclosed |
| US-4174323-A | BACTERICIDE, CEPHALOSPORIN INTERMEDIATES | SMITHKLINE CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |
| US-4174323-A | BACTERICIDE, CEPHALOSPORIN INTERMEDIATES | SMITHKLINE CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |
| EP-0000100-A1 | 7-Acylamino-3-(1-(2-sulfamoylaminoethyl)-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids, a process for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1978-12-20 | — | — | EP | disclosed |
| US-4117123-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4117123-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |