Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31074994 | 0.86 | KMT2A (0.61) | DRD4KMT2A | |
| SCHEMBL62620 | 0.86 | KMT2A (0.61) | DRD4KMT2A | |
| Hydrochloric Acid SCHEMBL3160630 | 0.84 | KMT2A (0.60) | DRD4KMT2A | |
| SCHEMBL27511688 | 0.77 | KMT2A (0.49) | CCNT1CDK9CDK5CDK5R1PARP1 | |
| SCHEMBL5038597 | 0.77 | KEAP1 (0.51) | CCNT1CDK9CDK5CDK5R1PARP1 | |
| SCHEMBL8124625 | 0.76 | PARP1 (0.47) | CCNT1CDK9CDK5CDK5R1PARP1 | |
| SCHEMBL31465178 | 0.75 | NPC1 (0.71) | CCNT1CDK9CDK5CDK5R1PARP1 | |
| Hydrochloric Acid SCHEMBL23360011 | 0.75 | PARP1 (0.52) | CCNT1CDK9CDK5CDK5R1PARP1 | |
| SCHEMBL28917070 | 0.75 | CDK2 (0.56) | CCNT1CDK9CDK5CDK5R1PARP1 | |
| SCHEMBL30088642 | 0.75 | TNKS (0.55) | CCNT1CDK9CDK5CDK5R1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304606-B | Degradation agent for simultaneously targeting BTK and GSPT proteins | 清华大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-115304606-A | Degradation agent for simultaneously targeting BTK and GSPT1 proteins | 清华大学 | 2022-11-08 | — | — | CN | disclosed |