Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23612075 | 0.94 | MGLL (0.50) | MGLLKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL29989203 | 0.90 | MGLL (0.54) | MGLLKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL23612088 | 0.90 | MGLL (0.54) | MGLLKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL23612218 | 0.86 | SCD (0.44) | MGLLALDH1A1MAPTNPC1TP53 | |
| SCHEMBL30089372 | 0.86 | SCD (0.44) | MGLLALDH1A1MAPTNPC1TP53 | |
| SCHEMBL23612244 | 0.85 | MGLL (0.47) | MGLLKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL5592199 | 0.84 | MGLL (0.50) | MGLLKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL5592097 | 0.80 | MGLL (0.54) | MGLLKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL23612028 | 0.78 | MGLL (0.52) | MGLLKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL29988816 | 0.78 | MGLL (0.52) | MGLLKDM1AMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085051-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2022-11-09 | — | — | EP | disclosed |