Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31239720 | 1.00 | TGM2 (1.00) | TGM2 | |
| SCHEMBL29988586 | 0.95 | TGM2 (1.00) | TGM2 | |
| SCHEMBL29989167 | 0.94 | TGM2 (1.00) | TGM2 | |
| SCHEMBL29988967 | 0.92 | TGM2 (1.00) | TGM2 | |
| SCHEMBL29988824 | 0.91 | TGM2 (1.00) | TGM2 | |
| SCHEMBL29988093 | 0.91 | TGM2 (1.00) | TGM2 | |
| SCHEMBL31239789 | 0.91 | TGM2 (1.00) | TGM2 | |
| SCHEMBL29989149 | 0.91 | TGM2 (1.00) | TGM2 | |
| SCHEMBL31239702 | 0.90 | TGM2 (1.00) | TGM2 | |
| SCHEMBL29988571 | 0.90 | TGM2 (1.00) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320106-A1 | ARYLACETYL INHIBITORS OF TG2 AND USES THEREOF | University Of Ottawa (CA) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022213198-A1 | ARYLACETYL INHIBITORS OF TG2 AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2022-10-13 | — | — | WO | disclosed |