Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20741559 | 0.82 | SYK (0.37) | SYKSSTR4SOS1PAX8CNR2 | |
| SCHEMBL30176186 | 0.82 | SYK (0.37) | SYKSSTR4SOS1PAX8CNR2 | |
| SCHEMBL20580580 | 0.82 | SSTR4 (0.38) | SYKSSTR4SOS1PAX8CNR2 | |
| SCHEMBL22175746 | 0.80 | SSTR4 (0.40) | SYKSSTR4BACE1BACE2GRM2 | |
| SCHEMBL24103634 | 0.78 | SSTR4 (0.43) | SYKSSTR4BACE1BACE2SOS1 | |
| SCHEMBL30420159 | 0.78 | SSTR4 (0.43) | SYKSSTR4BACE1BACE2SOS1 | |
| SCHEMBL29863332 | 0.78 | SSTR4 (0.35) | SYKSSTR4BACE1BACE2PAX8 | |
| SCHEMBL16753375 | 0.78 | SSTR4 (0.35) | SYKSSTR4BACE1BACE2PAX8 | |
| SCHEMBL3961865 | 0.77 | MAPT (0.35) | SYK | |
| SCHEMBL30176181 | 0.77 | MAPT (0.35) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022213980-A1 | TYK2 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2022-10-13 | — | — | WO | disclosed |