Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.60 |
| ▸ | WDR5 | P61964 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.60 |
| ▸ | NPY1R | P25929 | 2/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | HTR3A | P46098 | 2/20 | 0.60 |
| ▸ | FASN | P49327 | 2/20 | 0.60 |
| ▸ | SARM1 | Q6SZW1 | 2/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rabeprazole SCHEMBL2998947 | 1.00 | KMT2A (0.60) | KMT2ACYP2C9WDR5LMNAENGASE | |
| Rabeprazole SCHEMBL491358 | 1.00 | KMT2A (0.60) | KMT2ACYP2C9WDR5LMNAENGASE | |
| Dexrabeprazole SCHEMBL22189141 | 1.00 | KMT2A (0.60) | KMT2ACYP2C9WDR5LMNAENGASE | |
| Rabeprazole SCHEMBL140495 | 1.00 | KMT2A (0.60) | KMT2ACYP2C9WDR5LMNAENGASE | |
| Rabeprazole SCHEMBL27964348 | 0.99 | KMT2A (0.59) | KMT2ACYP2C9WDR5LMNAENGASE | |
| Dexrabeprazole SCHEMBL30945135 | 0.99 | KMT2A (0.61) | KMT2ACYP2C9WDR5LMNAENGASE | |
| Dexrabeprazole SCHEMBL30019061 | 0.99 | KMT2A (0.61) | KMT2ACYP2C9WDR5LMNAENGASE | |
| Dexrabeprazole SCHEMBL4946138 | 0.99 | KMT2A (0.61) | KMT2ACYP2C9WDR5LMNAENGASE | |
| Rabeprazole SCHEMBL29374701 | 0.99 | KMT2A (0.61) | KMT2ACYP2C9WDR5LMNAENGASE | |
| Rabeprazole SCHEMBL23336 | 0.99 | KMT2A (0.61) | KMT2ACYP2C9WDR5LMNAENGASE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114609268-B | Detection method for related substances in sodium rabeprazole bulk drug | 南京海纳医药科技股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-8247568-B2 | Process for the preparation of pure rabeprazole | MATRIX LABORATORIES LTD (IN) | 2012-08-21 | — | — | US | disclosed |
| US-20100190989-A1 | PROCESS FOR THE PREPARATION OF PURE RABEPRAZOLE | MATRIX LABORATORIES LTD (IN) | 2010-07-29 | — | — | US | disclosed |
| WO-2008155780-A2 | IMPROVED PROCESS FOR THE PREPARATION OF PURE RABEPRAZOLE | MATRIX LABORATORIES LTD (IN) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190989-A1 | PROCESS FOR THE PREPARATION OF PURE RABEPRAZOLE | RAB29, RAB35, RABL3 | KMT2A 2777/4885CYP2C9 34/4885WDR5 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.