Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29990073 | 0.88 | SMN1; SMN2 (0.39) | USP2SMN1; SMN2EPHX1EPHX2ALOX15 | |
| SCHEMBL29990387 | 0.85 | USP2 (0.38) | USP2SMN1; SMN2EPHX1EPHX2ALOX15 | |
| SCHEMBL29989714 | 0.85 | SMN1; SMN2 (0.38) | ALDH1A1USP2SMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL38657596 | 0.82 | KEAP1 (0.36) | USP2SMN1; SMN2EPHX1EPHX2ALOX15 | |
| SCHEMBL2800312 | 0.82 | USP2 (0.47) | USP2SMN1; SMN2EPHX1EPHX2ALOX15 | |
| SCHEMBL29989217 | 0.79 | SMN1; SMN2 (0.38) | USP2SMN1; SMN2EPHX1EPHX2ALOX15 | |
| SCHEMBL3923220 | 0.78 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2KMT2APOLBMAPT | |
| SCHEMBL1692872 | 0.76 | USP2 (0.47) | ALDH1A1USP2SMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL849290 | 0.75 | USP2 (0.50) | USP2SMN1; SMN2EPHX1EPHX2ALOX15 | |
| SCHEMBL1168818 | 0.75 | USP2 (0.50) | USP2SMN1; SMN2EPHX1EPHX2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234867-A1 | SULFONAMIDE HAVING MMP 7-INHIBITING ACTION | 大正製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |