Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013314 | 0.86 | HSD17B10 (0.53) | ALDH1A1HSD17B10KDM4EGAAMAPK1 | |
| SCHEMBL264389 | 0.85 | KDM4E (0.47) | ALDH1A1HSD17B10KDM4EGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL27984823 | 0.84 | KDM4E (0.46) | ALDH1A1HSD17B10KDM4EGAAMAPK1 | |
| SCHEMBL6401543 | 0.83 | KDM4E (0.54) | ALDH1A1HSD17B10KDM4EGAADPP4 | |
| SCHEMBL5500188 | 0.82 | KDM4E (0.55) | ALDH1A1HSD17B10KDM4EGAADPP4 | |
| SCHEMBL17854649 | 0.82 | DPP4 (0.49) | ALDH1A1HSD17B10KDM4EGAAMAPK1 | |
| SCHEMBL27889800 | 0.81 | KDM4E (0.71) | ALDH1A1HSD17B10KDM4EGAATSHR | |
| SCHEMBL25037588 | 0.80 | CYP1A2 (0.51) | ALDH1A1HSD17B10KDM4EGAADPP4 | |
| SCHEMBL17836948 | 0.80 | KDM4E (0.42) | ALDH1A1HSD17B10KDM4EGAAMAPK1 | |
| SCHEMBL3373962 | 0.80 | KDM4E (0.69) | ALDH1A1HSD17B10KDM4EGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133999-B2 | Process for preparation of 6, 7-bis(2-methoxyethoxy) quinazolin-4-one | UBE INDUSTRIES, LTD. (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20090253909-A1 | PROCESS FOR PREPARATION OF 6, 7-BIS (2-METHOXYETHOXY) QUINAZOLIN-4-ONE | UBE INDUSTRIES, LTD. (JP) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253909-A1 | PROCESS FOR PREPARATION OF 6, 7-BIS (2-METHOXYETHOXY) QUINAZOLIN-4-ONE | CYP4F11, OGFR, CYP4B1 | ALDH1A1 897/4885HSD17B10 3223/4885KDM4E 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.