⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915149 | 0.80 | TLR8 (0.31) | — | |
| SCHEMBL9755208 | 0.79 | — | — | |
| SCHEMBL3260107 | 0.76 | ALDH1A1 (0.37) | — | |
| SCHEMBL5683250 | 0.75 | — | — | |
| SCHEMBL7190966 | 0.72 | — | — | |
| SCHEMBL1515340 | 0.71 | — | — | |
| SCHEMBL4932093 | 0.71 | — | — | |
| SCHEMBL7469721 | 0.71 | — | — | |
| SCHEMBL732161 | 0.71 | — | — | |
| SCHEMBL5683854 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 768 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3474845-B1 | IMMUNOMODULATOR COMPOUNDS | CHEMOCENTRYX INC (US) | 2024-03-20 | — | — | EP | claimed |
| WO-2024039210-A1 | COMPOUNDS FOR INHIBITING OR DECOMPOSING CDK2 AND/OR CDK9, AND MEDICINAL USES THEREOF | 한국화학연구원 | 2024-02-22 | — | — | WO | claimed |
| CN-110325528-B | 2-benzopyrazinyl-N-heteroaryl-2-phenyl-acetamide compounds | 豪夫迈·罗氏有限公司 | 2022-10-11 | — | — | CN | claimed |
| EP-3664793-B1 | MACROCYCLIC IMMUNOMODULATORS | CHEMOCENTRYX INC (US) | 2022-06-29 | — | — | EP | claimed |
| CN-109803651-B | Immunomodulatory compounds | 凯莫森特里克斯股份有限公司 | 2022-05-31 | — | — | CN | claimed |
| EP-3996711-A1 | INDANES AS PD-L1 INHIBITORS | ChemoCentryx, Inc. (US) | 2022-05-18 | — | — | EP | claimed |
| US-11324826-B2 | Multifunctional treatment and diagnostic compositions and methods | ZAMADAR MATIBUR RAHAMAN (US) | 2022-05-10 | — | — | US | claimed |
| WO-2022001864-A1 | ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 昆山新蕴达生物科技有限公司 | 2022-01-06 | — | — | WO | claimed |
| WO-2021086312-A1 | REDUCED ADAPTIVE MICROBIAL RESISTANCE TREATMENT FOR FLESH EATING DISEASE | SALAZAR JENNIE (US) | 2021-05-06 | — | — | WO | claimed |
| US-20210121441-A1 | REDUCED ADAPTIVE MICROBIAL RESISTANCE TREATMENT FOR FLESH EATING DISEASE (necrotizing fasciitis) | ZAMADAR MATIBUR RAHAMAN (US) | 2021-04-29 | — | — | US | claimed |
| US-5281571-A | Herbicidal benzoxazinone- and benzothiazinone-substituted pyrazoles | MONSANTO COMPANY (US) | 1994-01-25 | — | — | US | claimed |
| US-5252732-A | D-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl and O-alkynylheteroarylmacrolides having immunosuppressive activity | MERCK & CO., INC. (US) | 1993-10-12 | — | — | US | claimed |
| US-5225562-A | Method of preparing (+)-deoxoartemisinin and selected analogues of (+)-deoxoartemisinin | MISSISSIPPI, THE UNIVERSITY OF | 1993-07-06 | — | — | US | claimed |
| EP-0145906-B1 | CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-11 | — | — | EP | claimed |
| EP-0400583-A1 | Imidazoquinoxalinones, their aza analogs and process for their preparation | BERLEX LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | claimed |
| EP-0354201-A2 | Safening herbicidal benzoic acid derivatives | MONSANTO COMPANY (US) | 1990-02-07 | — | — | EP | claimed |
| US-4886817-A | Imidazolidinones as brain activators | TANABE SEIYAKU CO., LTD. (JP) | 1989-12-12 | — | — | US | claimed |
| CN-1033991-A | SUBSTITUTED HYDROXYLAMINES | BAYER AG (DE) | 1989-07-19 | — | — | CN | claimed |
| US-4347365-A | ANTICONVULSANTS, MUSCLE RELAXANTS, SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1982-08-31 | — | — | US | claimed |
| US-4230713-A | ANXIOLYTIC AGENTS | ICI AMERICAS INC. (US) | 1980-10-28 | — | — | US | claimed |