Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28390672 | 1.00 | MAPT (0.59) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL14669363 | 0.84 | HPGD (0.47) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL1284461 | 0.78 | NPSR1 (0.58) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL16042060 | 0.78 | ALDH1A1 (0.63) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL30016904 | 0.78 | ALDH1A1 (0.63) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL7807160 | 0.77 | MAPT (0.69) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL5987289 | 0.77 | AR (0.62) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL2386906 | 0.73 | NPSR1 (0.66) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL29935405 | 0.73 | KDM4E (0.54) | MAPTKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL9676889 | 0.73 | KDM4E (0.54) | MAPTKDM4EPOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116485-B | Preparation method of 5, 6-bis (4-aminobenzyl) -2-trifluoromethyl-1H-benzimidazole | 山西大学 | 2022-11-11 | — | — | CN | claimed |
| CN-111116485-B | Preparation method of 5, 6-bis (4-aminobenzyl) -2-trifluoromethyl-1H-benzimidazole | 山西大学 | 2022-11-11 | — | — | CN | disclosed |