Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.53 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | GNPAT | O15228 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | CPA2 | P48052 | 1/20 | 0.51 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31609331 | 0.92 | MME (0.56) | OPRM1OPRD1GNPATRENMME | |
| SCHEMBL31119957 | 0.90 | BACE1 (0.49) | BACE1BACE2OPRM1OPRD1REN | |
| SCHEMBL23081569 | 0.90 | BACE1 (0.49) | BACE1BACE2OPRM1OPRD1REN | |
| SCHEMBL29886195 | 0.87 | BACE1 (0.55) | BACE1BACE2OPRM1OPRD1REN | |
| SCHEMBL17732678 | 0.85 | GNPAT (0.67) | GNPATMMECPA1ACE2 | |
| SCHEMBL30799905 | 0.85 | GNPAT (0.67) | GNPATMMECPA1ACE2 | |
| SCHEMBL30533197 | 0.85 | GNPAT (0.67) | GNPATMMECPA1ACE2 | |
| SCHEMBL30190513 | 0.85 | KEAP1 (0.67) | BACE1BACE2OPRM1OPRD1KEAP1 | |
| SCHEMBL7421185 | 0.85 | CPA1 (0.59) | BACE1BACE2GNPATMMECPA1 | |
| SCHEMBL31326264 | 0.84 | MME (0.69) | GNPATMMECPA1CPB1CPA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022241417-A1 | METHODS AND COMPOSITIONS FOR EXTENDING ORGAN AND TISSUE PRESERVATION | THE GENERAL HOSPITAL CORPORATION (US) | 2022-11-17 | — | — | WO | disclosed |