Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.86 |
| ▸ | DRD4 | P21917 | 7/20 | 0.79 |
| ▸ | DRD3 | P35462 | 7/20 | 0.79 |
| ▸ | HTR1A | P08908 | 2/20 | 0.74 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.74 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.74 |
| ▸ | CNR1 | P21554 | 1/20 | 0.74 |
| ▸ | DRD1 | P21728 | 1/20 | 0.74 |
| ▸ | ACHE | P22303 | 1/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | HTR2A | P28223 | 1/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.74 |
| ▸ | HRH1 | P35367 | 1/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.74 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682779 | 1.00 | DRD2 (0.86) | DRD2DRD4DRD3HTR1AADRA2A | |
| SCHEMBL1987776 | 1.00 | DRD2 (0.86) | DRD2DRD4DRD3HTR1AADRA2A | |
| SCHEMBL31556291 | 1.00 | DRD2 (0.86) | DRD2DRD4DRD3HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL3467871 | 0.99 | DRD2 (0.85) | DRD2DRD4DRD3HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL3467872 | 0.99 | DRD2 (0.85) | DRD2DRD4DRD3HTR1AADRA2A | |
| SCHEMBL2022870 | 0.93 | DRD2 (0.74) | DRD2DRD4DRD3HTR1AADRA2A | |
| SCHEMBL2020786 | 0.93 | DRD2 (0.74) | DRD2DRD4DRD3HTR1AADRA2A | |
| SCHEMBL2025316 | 0.93 | DRD2 (0.74) | DRD2DRD4DRD3HTR1AADRA2A | |
| SCHEMBL10642251 | 0.90 | DRD2 (0.76) | DRD2DRD4DRD3HTR1AADRA2A | |
| SCHEMBL29104174 | 0.90 | DRD2 (0.76) | DRD2DRD4DRD3HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110726786-B | HPLC separation analysis method for rotigotine and important intermediate thereof | 上海柏狮生物科技有限公司 | 2022-12-06 | — | — | CN | disclosed |