SCHEMBL29992907

SCHEMBL29992907

Clc1ccc2oc3c(-c4c5ccccc5c(-c5ccc(-c6nc7ccccc7n6-c6ccccc6)cc5)c5ccccc45)cccc3c2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.42
PDE10A Q9Y233 2/20 0.40
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
MAPKAPK2 P49137 1/20 0.38
RECQL P46063 1/20 0.38
HDAC1 Q13547 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
PRKACA P17612 1/20 0.37
RPS6KB1 P23443 1/20 0.37
GSK3B P49841 1/20 0.37
ROCK1 Q13464 1/20 0.37
GRIA1 P42261 1/20 0.37
CACNG8 Q8WXS5 1/20 0.37
CACNG2 Q9Y698 1/20 0.37
KDM4E B2RXH2 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28524116 1.00 PTGS2 (0.42) PTGS2PDE10AESR1ESR2MAPKAPK2
SCHEMBL28534593 0.86 ESR1 (0.38) PTGS2ESR1ESR2RECQLHDAC1
SCHEMBL21392557 0.86 ESR1 (0.49) PTGS2ESR1ESR2MAPKAPK2RECQL
SCHEMBL12612753 0.81 RECQL (0.42) PTGS2ESR1ESR2MAPKAPK2RECQL
SCHEMBL1994838 0.81 ESR1 (0.48) PTGS2ESR1ESR2RECQLHDAC1
SCHEMBL17246910 0.81 ESR1 (0.42) PTGS2ESR1ESR2RECQLHDAC1
SCHEMBL26345263 0.80 ESR1 (0.45) PTGS2ESR1ESR2RECQLHDAC1
SCHEMBL18999482 0.80 ESR1 (0.47) PTGS2PDE10AESR1ESR2RECQL
SCHEMBL17246949 0.80 ESR1 (0.43) PTGS2ESR1ESR2RECQLHDAC1
SCHEMBL15394505 0.79 ESR1 (0.52) PTGS2ESR1ESR2RECQLHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500397-B Organic electroluminescent material with dibenzofuran-connected anthracene core structure and preparation method and device thereof 武汉尚赛光电科技有限公司 2022-11-11 CN disclosed