Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24238657 | 1.00 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL24238678 | 0.86 | SMN1; SMN2 (0.44) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL29993116 | 0.86 | SMN1; SMN2 (0.44) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL22680141 | 0.84 | SMN1; SMN2 (0.48) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL22045425 | 0.79 | GRM1 (0.47) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL22680196 | 0.76 | KDM4E (0.48) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL29429460 | 0.76 | KDM4E (0.48) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL25276294 | 0.75 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL22680185 | 0.74 | LMNA (0.46) | MEN1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL29429469 | 0.74 | LMNA (0.46) | MEN1KMT2ASMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887372-B1 | FURTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2022-10-12 | — | — | EP | disclosed |