Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1257077 | 1.00 | MAPK1 (0.45) | MAPK1AAK1ALDH1A1S1PR3LMNA | |
| SCHEMBL16522670 | 0.90 | KMT2A (0.40) | MAPK1AAK1ALDH1A1S1PR3LMNA | |
| SCHEMBL30979514 | 0.90 | KMT2A (0.40) | MAPK1AAK1ALDH1A1S1PR3LMNA | |
| SCHEMBL23730750 | 0.85 | MAPK1 (0.45) | MAPK1ALDH1A1S1PR3LMNAKMT2A | |
| SCHEMBL31147933 | 0.84 | MAPK1 (0.44) | MAPK1ALDH1A1S1PR3KMT2AACACB | |
| SCHEMBL1255170 | 0.84 | MAPK1 (0.43) | MAPK1ALDH1A1S1PR3ACACBIDH1 | |
| SCHEMBL15912513 | 0.80 | MEN1 (0.43) | MAPK1ALDH1A1S1PR3KMT2AACACB | |
| SCHEMBL4206631 | 0.78 | LMNA (0.39) | MAPK1AAK1ALDH1A1LMNAKMT2A | |
| SCHEMBL3544099 | 0.77 | LMNA (0.37) | MAPK1S1PR3LMNAKMT2AFPR2 | |
| SCHEMBL2949119 | 0.77 | AAK1 (0.49) | AAK1S1PR3KMT2AACACBBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335374-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-11-11 | — | — | CN | disclosed |