Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28592078 | 1.00 | MAPT (0.50) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL14082011 | 0.86 | KDM4E (0.58) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL13421144 | 0.82 | HRH1 (0.41) | MEN1KMT2ACHRM2HTR1ACHRM1 | |
| SCHEMBL4095527 | 0.78 | HRH1 (0.49) | KDM4EMEN1KMT2ACHRM2HTR1A | |
| SCHEMBL14543489 | 0.78 | CCR1 (0.50) | MAPTKDM4ESMN1; SMN2TP53MEN1 | |
| SCHEMBL29479235 | 0.77 | KDM4E (0.74) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8209185 | 0.77 | KDM4E (0.74) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL15886688 | 0.74 | KDM4E (0.75) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28373617 | 0.74 | NPC1 (0.50) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL17255883 | 0.73 | ALDH1A1 (0.39) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185555-B | Pincer-shaped manganese complex and preparation method thereof, related ligand and preparation method thereof, catalyst composition and application | 河北农业大学 | 2022-11-11 | — | — | CN | disclosed |