SCHEMBL2999359

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3418298	0.86	ALDH1A1 (0.39)	KDM4EALDH1A1MAPTCYP1A2CYP2C19
	SCHEMBL3007939	0.85	TNIK (0.37)	MEN1KMT2AKDM4EALDH1A1MAPT
	SCHEMBL2995526	0.78	TNIK (0.40)	MEN1KMT2AKDM4EALDH1A1MAPT
	SCHEMBL3006253	0.77	TNIK (0.39)	MEN1KMT2AKDM4EALDH1A1MAPT
	SCHEMBL3006252	0.77	TNIK (0.37)	MEN1KMT2AKDM4EALDH1A1MAPT
	SCHEMBL3007943	0.76	TNIK (0.40)	MEN1KMT2AKDM4EALDH1A1MAPT
	SCHEMBL3419133	0.72	EZH2 (0.40)	KDM4EALDH1A1MAPTKCNH2SLC2A1
	SCHEMBL2995429	0.71	ALDH1A1 (0.41)	KDM4EALDH1A1MAPTBRD4SLC2A1
	SCHEMBL25924584	0.69	ALDH1A1 (0.48)	MEN1KMT2AKDM4EALDH1A1MAPT
	SCHEMBL3011386	0.69	ALDH1A1 (0.43)	KDM4EALDH1A1MAPTADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.