Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484701 | 0.77 | POLB (0.46) | POLBHDAC8SLC22A1PRCPGBA1 | |
| SCHEMBL31524991 | 0.67 | CHRNB2 (0.47) | — | |
| SCHEMBL17542064 | 0.65 | POLB (0.71) | POLBGBA1 | |
| SCHEMBL17542062 | 0.65 | POLB (0.71) | POLBGBA1 | |
| SCHEMBL13791895 | 0.65 | GBA1 (0.55) | GBA1 | |
| SCHEMBL4577960 | 0.65 | GBA1 (0.55) | GBA1 | |
| SCHEMBL12076803 | 0.65 | GBA1 (0.55) | GBA1 | |
| SCHEMBL13803916 | 0.65 | GBA1 (0.55) | GBA1 | |
| SCHEMBL13803960 | 0.65 | GBA1 (0.55) | GBA1 | |
| SCHEMBL27447761 | 0.65 | HDAC8 (0.50) | POLBHDAC8SLC22A1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440507-B | Compound as apoptosis protein inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |