SCHEMBL29994005

CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	PDCD1LG2	Q9BQ51	1/20	0.51

▸	CD274	Q9NZQ7	1/20	0.51

▸	BACE1	P56817	12/20	0.49

▸	CTSD	P07339	4/20	0.49

▸	KISS1R	Q969F8	3/20	0.46

▸	OPRM1	P35372	1/20	0.41

▸	OPRD1	P41143	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29710468	0.93	BACE1 (0.45)	PDCD1LG2CD274BACE1CTSDKISS1R
SCHEMBL31130634	0.89	PDCD1LG2 (0.63)	PDCD1LG2CD274BACE1CTSDKISS1R
SCHEMBL29384747	0.89	PDCD1LG2 (0.61)	PDCD1LG2CD274BACE1CTSDKISS1R
SCHEMBL29382890	0.89	PDCD1LG2 (0.61)	PDCD1LG2CD274BACE1CTSDKISS1R
SCHEMBL29695578	0.87	PDCD1LG2 (0.46)	PDCD1LG2CD274BACE1CTSD
SCHEMBL30114824	0.86	BACE1 (0.48)	PDCD1LG2CD274BACE1CTSDKISS1R
SCHEMBL29679898	0.86	PDCD1LG2 (0.48)	PDCD1LG2CD274BACE1CTSD
SCHEMBL30400738	0.86	PDCD1LG2 (0.46)	PDCD1LG2CD274BACE1CTSDKISS1R
SCHEMBL38663936	0.85	OPRM1 (0.49)	PDCD1LG2CD274BACE1CTSDKISS1R
SCHEMBL31474507	0.84	PDCD1LG2 (0.52)	PDCD1LG2CD274BACE1CTSDKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12435143-B2	Caninized antibodies against canine CTLA-4	INTERVET INC. (US)	2025-10-07	—	—	US	disclosed
US-20220251208-A1	Caninized Antibodies Against Canine CTLA-4	INTERVET INC. (US)	2022-08-11	—	—	US	disclosed