SCHEMBL29994013

SCHEMBL29994013

Cc1c(-c2cccnc2)[nH]c2ccc(CN)cc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.64
CYP11B2 P19099 1/20 0.64
TLR9 Q9NR96 2/20 0.51
CYP2A6 P11509 3/20 0.49
LOXL2 Q9Y4K0 1/20 0.47
TLR8 Q9NR97 2/20 0.44
TLR7 Q9NYK1 2/20 0.44
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
F2 P00734 1/20 0.42
MAP2K4 P45985 1/20 0.42
NTRK1 P04629 1/20 0.41
TUBB4A P04350 2/20 0.41
TUBB P07437 2/20 0.41
TUBA3C P0DPH7 2/20 0.41
TUBA1B P68363 2/20 0.41
TUBA4A P68366 2/20 0.41
TUBB4B P68371 2/20 0.41
TUBB3 Q13509 2/20 0.41
TUBB2A Q13885 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23704287 1.00 CYP11B1 (0.64) CYP11B1CYP11B2TLR9CYP2A6LOXL2
SCHEMBL11069030 0.81 CYP11B1 (0.56) CYP11B1CYP11B2TLR9MTNR1AMTNR1B
Hydrochloric Acid SCHEMBL11007766 0.80 CYP11B1 (0.55) CYP11B1CYP11B2TLR9MTNR1AMTNR1B
SCHEMBL1606346 0.80 CYP11B1 (0.69) CYP11B1CYP11B2TLR9TLR8TLR7
SCHEMBL1607053 0.80 CYP11B1 (0.69) CYP11B1CYP11B2TLR9TLR8TLR7
SCHEMBL23704134 0.80 TLR9 (0.48) CYP11B1CYP11B2TLR9TLR7F2
SCHEMBL1605727 0.80 CYP11B1 (0.69) CYP11B1CYP11B2TLR9TLR8TLR7
Hydrochloric Acid SCHEMBL1604927 0.79 CYP11B1 (0.68) CYP11B1CYP11B2TLR9TLR8TLR7
Hydrochloric Acid SCHEMBL1605472 0.79 CYP11B1 (0.68) CYP11B1CYP11B2TLR9TLR8TLR7
Hydrochloric Acid SCHEMBL1605347 0.79 CYP11B1 (0.68) CYP11B1CYP11B2TLR9TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115052860-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-06-21 CN disclosed
EP-4097084-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2022-12-07 EP disclosed
CN-115052860-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-09-13 CN disclosed