SCHEMBL29994487

SCHEMBL29994487

OCCOc1cc(-c2ccccc2)ccc1N1CC[C@H](Oc2ccc(C(F)(F)F)cn2)C1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ LIPG Q9Y5X9 12/20 0.61
▸ LIPE Q05469 7/20 0.47
▸ LPL P06858 5/20 0.43
▸ LIPC P11150 5/20 0.43
▸ MET P08581 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29935833 1.00 LIPG (0.61) LIPGLIPELPLLIPCMET
SCHEMBL23702939 1.00 LIPG (0.61) LIPGLIPELPLLIPCMET
SCHEMBL23708323 1.00 LIPG (0.61) LIPGLIPELPLLIPCMET
SCHEMBL23708105 1.00 LIPG (0.61) LIPGLIPELPLLIPCMET
SCHEMBL23702852 0.91 LIPG (0.64) LIPGLIPELPLLIPC
SCHEMBL26620398 0.91 LIPG (0.64) LIPGLIPELPLLIPC
SCHEMBL23707917 0.89 LIPG (0.61) LIPGLIPELPLLIPCMET
SCHEMBL29993969 0.89 LIPG (0.61) LIPGLIPELPLLIPCMET
SCHEMBL23703492 0.89 LIPG (0.61) LIPGLIPELPLLIPCMET
SCHEMBL23703491 0.89 LIPG (0.61) LIPGLIPELPLLIPCMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702672-A Compounds and compositions for treating skin disorders 卡玛瑞制药有限公司 2024-09-27 — — CN disclosed
CN-115335050-B Compounds and compositions for treating skin disorders 卡玛瑞制药有限公司 2024-05-17 — — CN disclosed
EP-4096661-A1 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS Kamari Pharma Ltd. (IL) 2022-12-07 — — EP disclosed
CN-115335050-A Compounds and compositions for treating skin conditions 卡玛瑞制药有限公司 2022-11-11 — — CN disclosed
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