Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 14/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.53 |
| ▸ | PDE4A | P27815 | 11/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18830718 | 1.00 | PDE4B (0.53) | PDE4BPDE4DPDE4APDE4CRIPK1 | |
| SCHEMBL27880771 | 0.81 | PDE4B (0.43) | PDE4BPDE4DPDE4APDE4CRIPK1 | |
| SCHEMBL2323354 | 0.80 | PDE4B (0.48) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL8069054 | 0.79 | ALDH1A1 (0.60) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL23982177 | 0.79 | PDE4D (0.56) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL131011 | 0.79 | PDE4B (0.56) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL8854690 | 0.79 | PDE4D (0.60) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1157286 | 0.79 | PDE4B (0.56) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL6879083 | 0.79 | PDE4B (0.60) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL28813439 | 0.79 | PDE4B (0.41) | PDE4BPDE4DPDE4APDE4CRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354862-A | Substituted azacyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-115197190-A | Novel plant flavone derivative and preparation method and application thereof | 中国海洋大学 | 2022-10-18 | — | — | CN | disclosed |