Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 11/20 | 0.52 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | LIPE | Q05469 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29995288 | 1.00 | LIPG (0.60) | LIPGHCRTR1HCRTR2HSD11B1LIPE | |
| SCHEMBL26620485 | 1.00 | LIPG (0.60) | LIPGHCRTR1HCRTR2HSD11B1LIPE | |
| SCHEMBL23702791 | 1.00 | LIPG (0.60) | LIPGHCRTR1HCRTR2HSD11B1LIPE | |
| SCHEMBL23708283 | 1.00 | LIPG (0.60) | LIPGHCRTR1HCRTR2HSD11B1LIPE | |
| SCHEMBL23703256 | 0.91 | LIPG (0.58) | LIPGHCRTR1HCRTR2HSD11B1LIPE | |
| SCHEMBL23707901 | 0.91 | LIPG (0.58) | LIPGHCRTR1HCRTR2HSD11B1LIPE | |
| SCHEMBL23708771 | 0.91 | LIPG (0.58) | LIPGHCRTR1HCRTR2HSD11B1LIPE | |
| SCHEMBL29994749 | 0.91 | LIPG (0.58) | LIPGHCRTR1HCRTR2HSD11B1LIPE | |
| SCHEMBL26774388 | 0.86 | HCRTR1 (0.47) | LIPGHCRTR1HCRTR2 | |
| SCHEMBL26774384 | 0.86 | HCRTR1 (0.47) | LIPGHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702672-A | Compounds and compositions for treating skin disorders | 卡玛瑞制药有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-115335050-B | Compounds and compositions for treating skin disorders | 卡玛瑞制药有限公司 | 2024-05-17 | — | — | CN | disclosed |
| EP-4096661-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | Kamari Pharma Ltd. (IL) | 2022-12-07 | — | — | EP | disclosed |
| CN-115335050-A | Compounds and compositions for treating skin conditions | 卡玛瑞制药有限公司 | 2022-11-11 | — | — | CN | disclosed |