Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 2/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | IL17A | Q16552 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16346768 | 1.00 | LOX (0.56) | LOXLOXL2CDK4CCND1CDK2 | |
| SCHEMBL14279344 | 0.84 | LOX (0.53) | LOXLOXL2CDK4CCND1CDK2 | |
| SCHEMBL1670067 | 0.82 | PARP1 (0.35) | LOXLOXL2CDK4CCND1CDK2 | |
| SCHEMBL30329118 | 0.82 | HCRTR1 (0.40) | LOXLOXL2GRM2 | |
| SCHEMBL26921239 | 0.81 | LOX (0.49) | LOXLOXL2LMNASMN1; SMN2S1PR1 | |
| SCHEMBL615622 | 0.80 | KCNQ2 (0.43) | LOXLOXL2FFAR1MMP12CA1 | |
| SCHEMBL2092744 | 0.79 | LOXL2 (0.67) | LOXLOXL2FFAR1ENPP2MMP12 | |
| SCHEMBL5793683 | 0.79 | RECQL (0.49) | LOXLOXL2CDK2FFAR1LMNA | |
| SCHEMBL29962624 | 0.79 | LOXL2 (0.49) | LOXL2CDK2FFAR1CA2CA9 | |
| SCHEMBL3116042 | 0.79 | CYP1A2 (0.39) | LOXLOXL2CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288433-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167819-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2022-08-11 | — | — | WO | disclosed |