Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | AADAC | P22760 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410168 | 1.00 | HRH1 (0.53) | HRH1ROCK1EPHX1SCN10AEPHX2 | |
| SCHEMBL1673897 | 0.94 | HRH1 (0.59) | HRH1EPHX1EPHX2FAAHAADAC | |
| Potassium Ion SCHEMBL3634494 | 0.90 | HRH1 (0.56) | HRH1EPHX1EPHX2FAAHAADAC | |
| SCHEMBL13703554 | 0.89 | HRH1 (0.54) | HRH1EPHX1EPHX2FAAHAADAC | |
| Hydrochloric Acid SCHEMBL4324971 | 0.88 | HRH1 (0.53) | HRH1EPHX1EPHX2FAAHAADAC | |
| SCHEMBL18960369 | 0.85 | EPHX2 (0.48) | EPHX1EPHX2FAAHAADACFPR2 | |
| SCHEMBL2300079 | 0.84 | CHRNB2 (0.49) | HRH1ROCK1EPHX1SCN10AHTR2C | |
| SCHEMBL19838848 | 0.82 | HRH1 (0.58) | HRH1ROCK1EPHX2HTR2CIKBKB | |
| SCHEMBL7657873 | 0.81 | EPHX2 (0.54) | EPHX2FAAHAADACFPR2PROKR1 | |
| SCHEMBL76222 | 0.79 | HRH1 (0.54) | HRH1ROCK1EPHX1EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210225-A | Substituted aminoquinolones as immuno-activated DGKALPHA inhibitors | 拜耳公司 | 2022-10-18 | — | — | CN | disclosed |