Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515140 | 0.92 | GPR119 (0.76) | GPR119 | |
| SCHEMBL515139 | 0.92 | GPR119 (0.79) | GPR119 | |
| SCHEMBL2717368 | 0.92 | GPR119 (0.72) | GPR119 | |
| SCHEMBL10255383 | 0.91 | GPR119 (0.84) | GPR119 | |
| SCHEMBL17091636 | 0.91 | GPR119 (0.67) | GPR119 | |
| SCHEMBL3238465 | 0.91 | GPR119 (0.77) | GPR119 | |
| SCHEMBL3237856 | 0.91 | GPR119 (0.74) | GPR119 | |
| SCHEMBL3511634 | 0.90 | GPR119 (0.81) | GPR119 | |
| SCHEMBL3242159 | 0.90 | GPR119 (0.79) | GPR119 | |
| SCHEMBL3238021 | 0.90 | GPR119 (0.75) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210886-B1 | PYRIMIDYL INDOLINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-09-23 | — | — | EP | claimed |
| EP-2445901-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS RELATING THERETO | Boehringer Ingelheim International GmbH (DE) | 2012-05-02 | — | — | EP | disclosed |
| EP-2427450-A1 | GPR 119 MODULATORS | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010149685-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS RELATING THERETO | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010128425-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |