Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29997377 | 0.85 | FGFR1 (0.53) | KDM4EADRB2CYP1A2CYP2C19HTR7 | |
| SCHEMBL28891200 | 0.85 | FGFR1 (0.53) | KDM4EADRB2CYP1A2CYP2C19HTR7 | |
| SCHEMBL10706756 | 0.84 | ADRB2 (0.65) | KDM4EADRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27610244 | 0.82 | KDM4E (0.51) | KDM4EADRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29997368 | 0.82 | KDM4E (0.51) | KDM4EADRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16180436 | 0.82 | KDM4E (0.51) | KDM4EADRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9148968 | 0.82 | KDM4E (0.51) | KDM4EADRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16180435 | 0.81 | KDM4E (0.57) | KDM4EADRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9561559 | 0.81 | SOAT1 (0.48) | KDM4EADRB2L3MBTL1LMNA | |
| SCHEMBL29997388 | 0.81 | CYP1A2 (0.42) | KDM4EADRB2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115361948-A | Methods and compositions for inhibiting dihydroorotate dehydrogenase | 俄亥俄州国家创新基金会 | 2022-11-18 | — | — | CN | disclosed |