SCHEMBL29997477

SCHEMBL29997477

Cn1c(C(F)(F)F)cc(=O)n(-c2nc(CO)c(Cl)cc2F)c1=O

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24634641 1.00 NPSR1 (0.31) NPSR1MEN1KMT2AALDH1A1
SCHEMBL29328672 0.85 BRD9 (0.30)
SCHEMBL7597082 0.85 GRM4 (0.31) NPSR1
SCHEMBL7595081 0.84 GAA (0.32) NPSR1MEN1KMT2A
SCHEMBL29435262 0.84 GAA (0.32) NPSR1MEN1KMT2A
SCHEMBL19641780 0.84 GAA (0.32) NPSR1MEN1KMT2A
SCHEMBL7595408 0.83 GAA (0.31) NPSR1MEN1KMT2A
SCHEMBL7601120 0.81 COMT (0.31)
SCHEMBL7607651 0.81 GAA (0.37) NPSR1MEN1KMT2AALDH1A1
SCHEMBL23635748 0.81 NPSR1 (0.31) NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4320122-A1 HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2024-02-14 EP disclosed
CN-117120437-A Herbicidal compounds 先正达农作物保护股份公司 2023-11-24 CN disclosed
WO-2022214377-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-10-13 WO disclosed