SCHEMBL7607651

SCHEMBL7607651

CCOC(=O)c1nc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.37
BAZ2B Q9UIF8 1/20 0.37
BAZ2A Q9UIF9 1/20 0.37
HSD17B10 Q99714 3/20 0.35
ALDH1A1 P00352 2/20 0.35
NPC1 O15118 1/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
XBP1 P17861 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TLR9 Q9NR96 1/20 0.35
GLP1R P43220 1/20 0.34
POLB P06746 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GABRA2 P47869 3/20 0.33
GABRB2 P47870 3/20 0.33
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28991747 0.83 PPOX (0.40) GAAMAPTNPSR1POLBL3MBTL1
SCHEMBL22941954 0.82 NPSR1 (0.37) GAAHSD17B10ALDH1A1NPC1TP53
SCHEMBL24961591 0.81 CDC7 (0.38) GAABAZ2BBAZ2AHSD17B10ALDH1A1
SCHEMBL29435264 0.81 KAT2B (0.36) BAZ2BBAZ2AMAPTPOLBL3MBTL1
SCHEMBL24634641 0.81 NPSR1 (0.31) ALDH1A1NPSR1MEN1KMT2A
SCHEMBL29997477 0.81 NPSR1 (0.31) ALDH1A1NPSR1MEN1KMT2A
SCHEMBL23664631 0.81 GAA (0.30) GAAATM
SCHEMBL6336900 0.80 BAZ2B (0.46) GAABAZ2BBAZ2AHSD17B10ALDH1A1
SCHEMBL7597082 0.80 GRM4 (0.31) GAANPSR1L3MBTL1ATM
SCHEMBL7595081 0.79 GAA (0.32) GAANPSR1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020156285-A1 Novel herbicides KUNZ WALTER (CH) 2002-10-24 US disclosed
US-6369002-B1 HETERO IS PYRIMIDINE OR PYRIDAZINE; 1-(3-FLUORO-5-CHLORO PYRIDIN-2-YL)-3-METHYL-4-TRIFLUOROMETHYLPYRIMIDIN-2,6-DIONE SYNGENTA CROP PROPERTIES, INC. 2002-04-09 US disclosed
EP-1076656-A2 N-HETEROARYL-SUBSTITUTED PYRIDINE DERIVATIVES AND THEIR USE AS HERBICIDES Novartis AG (CH) 2001-02-21 EP disclosed
WO-1999055693-A2 N-HETEROARYL-SUBSTITUTED PYRIDINE DERIVATIVES AND THEIR USE AS HERBICIDES NOVARTIS AG (CH) 1999-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020156285-A1 Novel herbicides DDT, CBR1, CBR3 GAA 3410/4885BAZ2B 3716/4885BAZ2A 3615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.