Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22013648 | 0.81 | TDP1 (0.58) | KDM4EPOLBAPEX1ALDH1A1GAA | |
| Tremetone SCHEMBL4743839 | 0.75 | POLB (0.75) | KDM4EPOLBAPEX1RECQLALDH1A1 | |
| Tremetone SCHEMBL4743840 | 0.75 | POLB (0.75) | KDM4EPOLBAPEX1RECQLALDH1A1 | |
| SCHEMBL3375377 | 0.73 | AKR1C3 (0.54) | ALOX5AKR1B10AKR1B1MMP2NFKB1 | |
| SCHEMBL3375374 | 0.73 | AKR1C3 (0.54) | ALOX5AKR1B10AKR1B1MMP2NFKB1 | |
| SCHEMBL29999634 | 0.73 | KDM4E (0.49) | KDM4EPOLBAPEX1ALDH1A1GAA | |
| SCHEMBL20594954 | 0.70 | POLB (0.52) | KDM4EPOLBAPEX1RECQLALDH1A1 | |
| SCHEMBL14898033 | 0.68 | KDM4E (0.50) | KDM4EPOLBAPEX1ALDH1A1GAA | |
| SCHEMBL21962337 | 0.68 | KDM4E (0.69) | KDM4EPOLBAPEX1ALDH1A1GAA | |
| SCHEMBL2717768 | 0.68 | KDM4E (0.69) | KDM4EPOLBAPEX1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4346810-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | Unigen, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022256624-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | UNIGEN, INC. (US) | 2022-12-08 | — | — | WO | disclosed |