Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999195 | 0.83 | PTPN1 (0.45) | KDM4EPTPN1GAAMGAMSI | |
| SCHEMBL29216337 | 0.83 | PTPN1 (0.45) | KDM4EPTPN1GAAMGAMSI | |
| SCHEMBL9101771 | 0.80 | KDM4E (0.52) | KDM4EESR1ESR2PTPN1GAA | |
| SCHEMBL9101781 | 0.80 | KDM4E (0.52) | KDM4EESR1ESR2PTPN1GAA | |
| SCHEMBL14898033 | 0.77 | KDM4E (0.50) | KDM4EPTPN1GAAALOX5HSD17B10 | |
| SCHEMBL22013648 | 0.77 | TDP1 (0.58) | KDM4EPTPN1GAAALOX5HSD17B10 | |
| SCHEMBL15397966 | 0.74 | AKR1C3 (0.54) | PTPN1ALOX5AKR1B10AKR1B1MMP2 | |
| SCHEMBL15397968 | 0.74 | AKR1C3 (0.54) | PTPN1ALOX5AKR1B10AKR1B1MMP2 | |
| SCHEMBL7597293 | 0.74 | KDM4E (0.52) | KDM4EESR1ESR2PTPN1GAA | |
| SCHEMBL7597289 | 0.74 | KDM4E (0.52) | KDM4EESR1ESR2PTPN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4346810-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | Unigen, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022256624-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | UNIGEN, INC. (US) | 2022-12-08 | — | — | WO | disclosed |