Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 3/20 | 0.57 |
| ▸ | SKP1 | P63208 | 3/20 | 0.57 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448755 | 1.00 | CKS1B (0.57) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL27451694 | 0.85 | CKS1B (0.53) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL21564567 | 0.84 | CKS1B (0.60) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL30931783 | 0.84 | CKS1B (0.60) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL27449378 | 0.83 | SUV39H2 (0.53) | CKS1BSKP1SKP2SUV39H2BTK | |
| SCHEMBL21564375 | 0.82 | CKS1B (0.56) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL32665202 | 0.82 | CKS1B (0.52) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL12321963 | 0.81 | CKS1B (0.53) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL21390074 | 0.81 | CKS1B (0.50) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL29998716 | 0.80 | CKS1B (0.48) | CKS1BSKP1SKP2SUV39H2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304549-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
| EP-4509500-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | Sichuan Huiyu Pharmaceutical Co., Ltd. (CN) | 2025-02-19 | — | — | EP | disclosed |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| WO-2023222115-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | 四川汇宇制药股份有限公司 | 2023-11-23 | — | — | WO | disclosed |
| WO-2022199662-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | 四川汇宇制药股份有限公司 | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304549-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | HDAC1, HDAC11, HDAC5 | CKS1B 2237/4885SKP1 1921/4885SKP2 1815/4885 |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | KDM1A, TET1, KDM3A | CKS1B 808/4885SKP1 331/4885SKP2 695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.