⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439424 | 1.00 | — | — | |
| SCHEMBL18327727 | 0.77 | — | — | |
| SCHEMBL7216828 | 0.77 | — | — | |
| SCHEMBL5809339 | 0.77 | — | — | |
| SCHEMBL29773795 | 0.76 | TRIM24 (0.61) | — | |
| 2-Chloronicotinaldehyde SCHEMBL715765 | 0.74 | — | — | |
| SCHEMBL346904 | 0.74 | TRIM24 (0.59) | — | |
| 2-Chloronicotinaldehyde SCHEMBL29828177 | 0.74 | — | — | |
| SCHEMBL881418 | 0.74 | — | — | |
| SCHEMBL20070416 | 0.74 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365594-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
| US-20220389034-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2022-12-08 | — | — | US | disclosed |