⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999963 | 1.00 | — | — | |
| SCHEMBL18327727 | 0.77 | — | — | |
| SCHEMBL7216828 | 0.77 | — | — | |
| SCHEMBL5809339 | 0.77 | — | — | |
| SCHEMBL29773795 | 0.76 | TRIM24 (0.61) | — | |
| 2-Chloronicotinaldehyde SCHEMBL715765 | 0.74 | — | — | |
| SCHEMBL346904 | 0.74 | TRIM24 (0.59) | — | |
| 2-Chloronicotinaldehyde SCHEMBL29828177 | 0.74 | — | — | |
| SCHEMBL881418 | 0.74 | — | — | |
| SCHEMBL20070416 | 0.74 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707612-A | Preparation method of gamma-deuterated amino acid ester | 浙大宁波理工学院 | 2025-03-28 | — | — | CN | claimed |
| US-12178802-B1 | 3-(1-(3-(dimethylamino)propyl)-4,5-diphenyl-1H-imidazol-2-yl)pyridin-2-ol as an antitumor and antimicrobial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | claimed |
| US-12134622-B1 | 2-benzo-[3,4-b]pyridine-[b,g]indeno[1,2;3,4]fluoreno-[1,2-d]oxonine-5,11,16,21-tetraone as an antimicrobial compound | King Faisal University (SA) | 2024-11-05 | — | — | US | claimed |
| US-12129241-B1 | 9-(2-hydroxypyridin-3-yl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound | King Faisal University (SA) | 2024-10-29 | — | — | US | claimed |
| CN-118459299-A | Gamma site deuteration method of fatty amine compound | 浙大宁波理工学院 | 2024-08-09 | — | — | CN | claimed |
| US-11987570-B1 | 10-(2-hydroxyethyl)-9-(2-hydroxypyridin-3-yl)-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione as an antimicrobial compound | King Faisal University (SA) | 2024-05-21 | — | — | US | claimed |
| CN-117969421-A | Universal sensor and method for identifying absolute configuration and optical purity of beta-chiral primary amine | 中国医学科学院药物研究所 | 2024-05-03 | — | — | CN | claimed |
| CN-116425647-B | Preparation method of alpha-deuterated amino acid methyl ester | 浙大宁波理工学院 | 2024-04-02 | — | — | CN | claimed |
| US-11945793-B1 | 9-(2-hydroxypyridin-3-yl)-10[3-(dimethylamino)propyl]-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione as an antimicrobial compound | King Faisal University (SA) | 2024-04-02 | — | — | US | claimed |
| US-11939315-B1 | Ethyl 2-[9-(2-hydroxypyridin-3-yl)-3,6-diphenyl-1,8-dioxo-3,4,9,10-tetrahydroacridine-10-yl]-acetate as an antimicrobial compound | King Faisal University (SA) | 2024-03-26 | — | — | US | claimed |
| US-20050267044-A1 | Novel compounds and compositions as cathepsin S inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-01 | — | — | US | claimed |
| US-6900237-B2 | Sulfonamide compounds as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-05-31 | — | — | US | claimed |
| CN-1585757-A | Oligopeptides and compositions containing them as cathepsin S inhibitors | AVENTIS PHARMA INC (US) | 2005-02-23 | — | — | CN | claimed |
| CN-1553892-A | Novel compounds and compositions as cathepsin inhibitors | ����˹��ҩ�﹫˾ | 2004-12-08 | — | — | CN | claimed |
| US-20040192742-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. | 2004-09-30 | — | — | US | claimed |
| EP-1446392-A1 | OLIGOPEPTIDES AND COMPOSITIONS CONTAINING THEM AS CATHEPSIN S INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2004-08-18 | — | — | EP | claimed |
| US-20030199506-A1 | Novel compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS INC. | 2003-10-23 | — | — | US | claimed |
| US-20030158231-A1 | Sulfonamide compounds as protease inhibitors | Celera Corporation | 2003-08-21 | — | — | US | claimed |
| WO-2003042197-A1 | OLIGOPEPTIDES AND COMPOSITIONS CONTAINING THEM AS CATHEPSIN S INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-05-22 | — | — | WO | claimed |
| WO-2003024923-A1 | SULFONAMIDE COMPOUNDS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-03-27 | — | — | WO | claimed |