Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 7/20 | 0.39 |
| ▸ | NOS1 | P29475 | 6/20 | 0.39 |
| ▸ | NOS3 | P29474 | 3/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25389761 | 1.00 | NSD2 (0.45) | NSD2MAPTQDPRPRMT5WDR77 | |
| SCHEMBL25388838 | 0.88 | NSD2 (0.43) | NSD2MAPTPRMT5WDR77NOS2 | |
| SCHEMBL30000062 | 0.88 | NSD2 (0.43) | NSD2MAPTPRMT5WDR77NOS2 | |
| SCHEMBL29501351 | 0.87 | NSD2 (0.42) | NSD2MAPTPRMT5WDR77NOS2 | |
| SCHEMBL22549439 | 0.87 | NSD2 (0.42) | NSD2MAPTPRMT5WDR77NOS2 | |
| SCHEMBL27172393 | 0.85 | NSD2 (0.45) | NSD2MAPTPRMT5WDR77NOS2 | |
| SCHEMBL29999584 | 0.85 | NSD2 (0.45) | NSD2MAPTPRMT5WDR77NOS2 | |
| SCHEMBL27172459 | 0.85 | MAPT (0.45) | NSD2MAPTPRMT5WDR77NOS2 | |
| SCHEMBL30000118 | 0.85 | MAPT (0.45) | NSD2MAPTPRMT5WDR77NOS2 | |
| SCHEMBL23304428 | 0.84 | GBA1 (0.46) | NSD2MAPTPRMT5WDR77NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113626-A | Compound with anti-tumor activity and application thereof | 上海翊石医药科技有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2022237858-A1 | COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-11-17 | — | — | WO | disclosed |
| CN-115340528-A | Compound with anti-tumor activity and application thereof | 上海翊石医药科技有限公司 | 2022-11-15 | — | — | CN | disclosed |