Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | SORD | Q00796 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635340 | 0.78 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL24744626 | 0.76 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL21802224 | 0.75 | MCL1 (0.45) | MEN1KMT2ASMN1; SMN2L3MBTL1MMP13 | |
| SCHEMBL19615367 | 0.75 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL19615199 | 0.73 | MCL1 (0.41) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL21802226 | 0.73 | MCL1 (0.44) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| Acetic Acid SCHEMBL28656086 | 0.73 | MCL1 (0.46) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL28656085 | 0.71 | MCL1 (0.42) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL19615186 | 0.71 | MEN1 (0.66) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL14924450 | 0.70 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255888-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |