Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 11/20 | 0.77 |
| ▸ | GSK3B | P49841 | 1/20 | 0.77 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695893 | 1.00 | WNT3A (0.77) | WNT3AGSK3BMTORSORT1NPC1 | |
| SCHEMBL24695895 | 0.92 | WNT3A (0.77) | WNT3AGSK3BMTORSORT1NPC1 | |
| SCHEMBL30002006 | 0.92 | WNT3A (0.77) | WNT3AGSK3BMTORSORT1NPC1 | |
| SCHEMBL20604145 | 0.90 | WNT3A (0.80) | WNT3AGSK3BMTORNPC1RAB9A | |
| SCHEMBL30387465 | 0.90 | WNT3A (0.80) | WNT3AGSK3BMTORNPC1RAB9A | |
| SCHEMBL24695178 | 0.89 | WNT3A (0.79) | WNT3AGSK3BMTORSORT1NPC1 | |
| SCHEMBL20604123 | 0.88 | WNT3A (0.77) | WNT3AGSK3BMTORSORT1NPC1 | |
| SCHEMBL20604161 | 0.87 | WNT3A (1.00) | WNT3AGSK3BMTORNPC1RAB9A | |
| SCHEMBL30001809 | 0.87 | WNT3A (1.00) | WNT3AGSK3BMTORNPC1RAB9A | |
| SCHEMBL30388050 | 0.87 | WNT3A (1.00) | WNT3AGSK3BMTORNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4346811-A1 | DUAL WNT SIGNALING PATHWAY INHIBITORS AND AMPK ACTIVATORS FOR TREATMENTS OF DISEASE | University of Maryland, Baltimore (US) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022256419-A1 | DUAL WNT SIGNALING PATHWAY INHIBITORS AND AMPK ACTIVATORS FOR TREATMENTS OF DISEASE | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2022-12-08 | — | — | WO | disclosed |