Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23455521 | 1.00 | ITGB1 (0.53) | ITGB1ITGA5PRMT5WDR77KAT6A | |
| SCHEMBL23455519 | 1.00 | ITGB1 (0.53) | ITGB1ITGA5PRMT5WDR77KAT6A | |
| SCHEMBL23455393 | 0.95 | ITGB1 (0.49) | ITGB1ITGA5PRMT5WDR77KAT6A | |
| SCHEMBL30001027 | 0.95 | ITGB1 (0.49) | ITGB1ITGA5PRMT5WDR77KAT6A | |
| SCHEMBL23455394 | 0.95 | ITGB1 (0.49) | ITGB1ITGA5PRMT5WDR77KAT6A | |
| SCHEMBL23455439 | 0.93 | ITGB1 (0.64) | ITGB1ITGA5PRMT5WDR77KAT6A | |
| SCHEMBL28884201 | 0.92 | ITGB1 (0.62) | ITGB1ITGA5PRMT5WDR77KAT6A | |
| SCHEMBL23455488 | 0.89 | ITGB1 (0.52) | ITGB1ITGA5PRMT5WDR77NPC1 | |
| SCHEMBL23455487 | 0.89 | ITGB1 (0.52) | ITGB1ITGA5PRMT5WDR77NPC1 | |
| SCHEMBL23455485 | 0.89 | ITGB1 (0.52) | ITGB1ITGA5PRMT5WDR77NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4072541-A1 | ALPHA-5 BETA-1 INHIBITORS | The Regents of the University of California (US) | 2022-10-19 | — | — | EP | disclosed |