Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.54 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.51 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053553 | 0.95 | SLC6A2 (0.63) | SLC6A2OPRM1OPRD1 | |
| SCHEMBL9052421 | 0.95 | SLC6A2 (0.63) | SLC6A2OPRM1OPRD1 | |
| SCHEMBL30289679 | 0.90 | SLC6A2 (0.58) | SLC6A2CALCRLRAMP1OPRM1OPRD1 | |
| SCHEMBL30630359 | 0.89 | SLC6A2 (0.48) | SLC6A2CALCRLRAMP1ACEOPRM1 | |
| SCHEMBL29589468 | 0.87 | ACE (0.71) | ACEACE2 | |
| SCHEMBL30503063 | 0.86 | SLC6A2 (0.53) | SLC6A2OPRM1OPRD1 | |
| SCHEMBL29579276 | 0.86 | CALCRL (0.52) | SLC6A2CALCRLRAMP1OPRM1OPRD1 | |
| SCHEMBL31412199 | 0.86 | OPRM1 (0.66) | SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL30833622 | 0.86 | OPRM1 (0.66) | SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL29702054 | 0.86 | OPRM1 (0.66) | SLC6A2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395373-B1 | METHOD FOR LABELLING A BIOLOGICAL TARGETING MOLECULE VIA CONJUGATION WITH A RADIOISOTOPE SUITABLE FOR PET OR SPECT IMAGING | GE HEALTHCARE LTD (GB) | 2022-10-19 | — | — | EP | claimed |
| EP-3395373-B1 | METHOD FOR LABELLING A BIOLOGICAL TARGETING MOLECULE VIA CONJUGATION WITH A RADIOISOTOPE SUITABLE FOR PET OR SPECT IMAGING | GE HEALTHCARE LTD (GB) | 2022-10-19 | — | — | EP | disclosed |