Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10637065 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL1238242 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL6238375 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL21806304 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL7527682 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL10630506 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL1695866 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL4894483 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL27855554 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL11579190 | 0.93 | FFAR3 (0.50) | FFAR3LCKFYNTP53SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578093-B1 | FILTER FOR CIGARETTE, AND CIGARETTE | JAPAN TOBACCO INC (JP) | 2018-10-03 | — | — | EP | claimed |
| EP-1470811-B1 | Composition comprising a dispersion of polymer particles and an ester of a carboxylic acid with a polyol for pigment dispersion | OREAL (FR) | 2006-05-03 | — | — | EP | claimed |
| EP-1470811-A1 | Composition comprising a dispersion of polymer particles and an ester of a carboxylic acid with a polyol for pigment dispersion | L'OREAL (FR) | 2004-10-27 | — | — | EP | claimed |
| WO-2012005347-A1 | EMULSIFYING COMPOSITION, PRODUCTION METHOD THEREOF AND FOOD AND DRINK PRODUCTS THAT CONTAIN SAME | 長谷川香料株式会社 (JP) | 2012-01-12 | — | — | WO | disclosed |
| EP-2373284-A2 | COSMETIC COMPOSITION FOR MAKEUP AND/OR KERATIN MATERIAL CARE, BASED ON A MIXTURE OF RESINS MQ AND T-PR, AND MAKEUP METHOD | L'Oréal (FR) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010063966-A9 | COSMETIC COMPOSITION FOR MAKEUP AND/OR KERATIN MATERIAL CARE, BASED ON A MIXTURE OF RESINS MQ AND T-PR, AND MAKEUP METHOD | L'OREAL (FR) | 2010-10-14 | — | — | WO | disclosed |
| EP-2229218-A2 | COSMETIC MAKE-UP AND/OR CARE METHOD USING A SILOXANE RESIN AND A FILM-FORMING POLYMER | L'Oréal (FR) | 2010-09-22 | — | — | EP | disclosed |
| WO-2010063966-A2 | COSMETIC COMPOSITION FOR MAKEUP AND/OR KERATIN MATERIAL CARE, BASED ON A MIXTURE OF RESINS MQ AND T-PR, AND MAKEUP METHOD | L'OREAL (FR) | 2010-06-10 | — | — | WO | disclosed |
| WO-2009080960-A2 | COSMETIC MAKE-UP AND/OR CARE METHOD USING A SILOXANE RESIN AND A FILM-FORMING POLYMER | L'OREAL (FR) | 2009-07-02 | — | — | WO | disclosed |
| EP-1452164-B1 | Double layer cosmetic product, its uses, and make-up kit comprising this product | OREAL (FR) | 2007-12-12 | — | — | EP | disclosed |
| EP-1470811-B1 | Composition comprising a dispersion of polymer particles and an ester of a carboxylic acid with a polyol for pigment dispersion | OREAL (FR) | 2006-05-03 | — | — | EP | disclosed |
| EP-1604633-A2 | Hard-wearing composition containing polymer particles dispersed in a fatty phase | L'OREAL (FR) | 2005-12-14 | — | — | EP | disclosed |
| EP-1604636-A2 | Cosmetic composition containing a non-polar wax and a dispersion of polymer particles in a fatty phase | L'OREAL (FR) | 2005-12-14 | — | — | EP | disclosed |
| EP-1604635-A2 | Composition containing polymer particles dispersed in a fatty phase and a non-polar oil | L'OREAL (FR) | 2005-12-14 | — | — | EP | disclosed |
| EP-1604637-A2 | Cosmetic composition containing a semicrystalline polymer and a dispersion of polymer particles in a fatty phase | L'OREAL (FR) | 2005-12-14 | — | — | EP | disclosed |
| EP-1477153-A1 | Cosmetic composition comprising a dispersion of polymer particles with it's plasticizer | L'OREAL (FR) | 2004-11-17 | — | — | EP | disclosed |
| EP-1470811-A1 | Composition comprising a dispersion of polymer particles and an ester of a carboxylic acid with a polyol for pigment dispersion | L'OREAL (FR) | 2004-10-27 | — | — | EP | disclosed |
| WO-2004078106-A2 | COSMETIC COMPOSITION COMPRISING A SEMI-CRYSTALLINE POLYMER AND A DISPERSION OF POLYMER PARTICLES IN AN OILY PHASE | L'OREAL (FR) | 2004-09-16 | — | — | WO | disclosed |
| EP-1452165-A2 | Bilayered make-up product, its uses and make-up kit containing this product | L'OREAL (FR) | 2004-09-01 | — | — | EP | disclosed |
| EP-1452164-A1 | Double layer cosmetic product, its uses, and make-up kit comprising this product | L'OREAL (FR) | 2004-09-01 | — | — | EP | disclosed |