Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086543 | 1.00 | GPR119 (0.45) | GPR119KCNH2 | |
| SCHEMBL27086546 | 1.00 | GPR119 (0.45) | GPR119KCNH2 | |
| SCHEMBL27086694 | 0.92 | GPR119 (0.37) | GPR119KCNH2 | |
| SCHEMBL27086689 | 0.92 | GPR119 (0.37) | GPR119KCNH2 | |
| SCHEMBL23215668 | 0.88 | GPR119 (0.43) | GPR119KCNH2 | |
| SCHEMBL29843726 | 0.88 | GPR119 (0.43) | GPR119KCNH2 | |
| SCHEMBL23215665 | 0.88 | GPR119 (0.43) | GPR119KCNH2 | |
| SCHEMBL30002042 | 0.86 | GPR119 (0.47) | GPR119KCNH2 | |
| SCHEMBL27086585 | 0.86 | GPR119 (0.47) | GPR119KCNH2 | |
| SCHEMBL27086537 | 0.82 | GPR119 (0.49) | GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320129-A1 | GPR119 AGONISTS | Kallyope, Inc. (US) | 2024-02-14 | — | — | EP | claimed |
| WO-2022216709-A1 | GPR119 AGONISTS | KALLYOPE, INC. (US) | 2022-10-13 | — | — | WO | claimed |
| US-20240217983-A1 | GPR119 AGONISTS | KALLYOPE, INC. | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217983-A1 | GPR119 AGONISTS | GPR119, GLP1R, GCGR | GPR119 1/4885KCNH2 4507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.