Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994348 | 1.00 | DPP4 (0.32) | DPP4DPP7KMT2AALOX5 | |
| SCHEMBL19994376 | 1.00 | DPP4 (0.32) | DPP4DPP7KMT2AALOX5 | |
| SCHEMBL3830274 | 0.77 | KMT2A (0.31) | KMT2A | |
| SCHEMBL24774089 | 0.76 | MAPK1 (0.35) | KMT2A | |
| SCHEMBL16027795 | 0.76 | MAPK1 (0.35) | KMT2A | |
| SCHEMBL16027794 | 0.76 | MAPK1 (0.35) | KMT2A | |
| SCHEMBL5066726 | 0.72 | MTNR1A (0.42) | KMT2AALOX5 | |
| SCHEMBL12059178 | 0.71 | — | — | |
| SCHEMBL24707475 | 0.71 | — | — | |
| SCHEMBL21358976 | 0.69 | DPP4 (0.39) | DPP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347032-A1 | SUBSTITUTED TETRAHYDROFURAN-2-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022256702-A1 | SUBSTITUTED TETRAHYDROFURAN-2-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-12-08 | — | — | WO | disclosed |